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HDEP-28 or Ethylnaphthidate is a piperidine based stimulant drug, closely related to Ethylphenidate, but with the benzene ring replaced by naphthalene. HDEP-28 is even more closely related to HDMP-28, which acts as a potent serotonin–norepinephrine–dopamine reuptake inhibitor with several times the potency of Methylphenidate and a short duration of action. HDEP-28 (Ethylnaphthidate) is a new research chemical with the IUPAC or formal name of ethyl 2-(naphthalen-2-yl)-2-(piperidin-2-yl)acetate, chemical formula of C19H23NO2, and a molecular mass of 297.40.
It is a structural analog of the widely-prescribed ADHD medication methylphenidate and is reported to produce near identical cognitive and physical effects, albeit with less of a euphoric “rush” component and a drawn-out duration of action, properties that many find preferable for use as a study-aid or productivity enhancer. Depending on the ROA the time of action is variable. Snorting common doses can feel similar to cocaine, while swallowing larger doses procuces effecs similar to MDMA.
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MDEP-28 has never been studies scientifically, therefore it is advised to follow hardm reduction practices.
MDEP-28has an extremely short history of recreational use in human and has yet to be documented being sold on the streets. It was initially released following the banning of ethylphenidate, which on April 2012 became illegal in the United Kingdom following a temporary-then-permanent blanket ban. Shortly after, it became made available for sale on the online gray market as a research chemical for global distribution.
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Isopropylphenidate is a synthetic molecule of the substituted phenethylamine and piperidine classes. It contains a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group via an ethyl chain. It is structurally similar to amphetamine, featuring a substitution at Rα which is then incorporated into a piperidine ring ending at the terminal amine of the phenethylamine chain. Additionally, it contains an isopropyl acetate bound to R2 of its molecular structure, a noticeable departure from methylphenidate, which contains a methyl group in this position.
